SF Fibrosis Conference, 2018

2018 Conference

SF Fibrosis Conference, 2018

The role of the fibrotic stroma - barrier or support?

Photo:

Elisabeth Hove

1/13

Donald Gullberg at the SF conference 2018

Photo:

Elisabeth Hove

2/13

Christhopher McCulloch at the SF conference 2018

Photo:

Donald Gullberg

3/13

Photo:

Donald Gullberg

4/13

Photo:

Donald Gullberg

5/13

Photo:

Donald Gullberg

6/13

Photo:

Donald Gullberg

7/13

Photo:

Donald Gullberg

8/13

Photo:

Donald Gullberg

9/13

Photo:

Donald Gullberg

10/13

Photo:

Donald Gullberg

11/13

Photo:

Elisabeth Hove

12/13

Photo:

San Fransisco from Marin Headlands

13/13

Main content

SIU Fibrosis conference, June 7-8, 2018

San Francisco

Venue:

Organizers: Donald Gullberg and Valerie Weaver

June 7th	Session 1a. Cell-ECM interactions - Chair: C.McCulloch (UoT)	Notes
8.30 鈥� 9.10am	1. Donald Gullberg, University of Bergen Integrin 伪11尾1 - a fibroblast protein with a role in fibrosis	听
9.15 鈥� 9.55am	2. Andrew Leask, University of Western Ontario Fibroblast-specific expression of CCN2 is required for activation of cancer asssociated-fibroblasts, angiogenesis and metastasis in a murine mode of melanoma	External
10.00-10.20am	Coffee	听
听	Session 1b. Cell-ECM interactions - Chair: D.Gullberg (UiB, UCSF)	听
10.20-11.00am	3. Christopher McCulloch, University of Toronto Role of Flightless in Remodeling of the Fibrotic Stroma	听
11.05-11.45am	4. Boris Hinz, University of Toronto Macrophage-Myofibroblast (Mis-) Communication	External
11.50-12.30	5. Dean Sheppard, UCSF Targeting TGFbeta-activing integrins to treat tissue fibrosis and cancer	听
12.35-1.00pm	Lunch	听
听	Session 2a. Tumor stroma associated fibrosis - Chair: V.Weaver (UCSF)	听
1.00-1.40pm	6. Roya Navab, University of Toronto Desmoplasia is associated with poor prognosis and carcinoma-associated fibroblasts heterogeneity in non-small cell lung cancer	听
1.45-2.25pm	7. Valerie Weaver, UCSF Tumor stiffness and hypoxia	听
2.30-3.05pm	8. Neil Bhowmick, Cedars Sinail Medical Centre, LA The role of glutamine in fibroblastic activation and tumor progression	External
3.10-3.25pm	Coffee	听
听	Session 2b. Tumor stroma associated fibrosis - Chair: D. Sheppard (UCSF)	听
3.25-4.05pm	9. Zena Werb, UCSF Tissue fibrosis and hypoxia in aggressive, basal-like breast cancers	听
4.10-4.50pm	10. Tushar Desai, Stanford Mapping Wnt signaling niches at cellular resolution in intact lung听during IPF progression	External
4.55-5.30pm	Business meeting SIU - Upcoming student exchanges	听
7.00 pm	Dinner 鈥� for speakers and some other invited guests	听
June 8th	Session 3a. Mechanisms of fibrosis - Chair: B. Hinz (UoT)	听
8.30 - 9.10am	11. Ari Molofsky, UCSF Mesenchymal - immune crosstalk at lymphocyte tissue niches	听
9.15 - 9.55am	12. Yang Chen, MD Anderson Cancer Centre, Houston Fibrosis and Cancer Metastasis	External
10.00-10.20am	Coffee	听
听	Session 3b. Mechanisms of fibrosis - Chair: R. Navab (UoT)	听
10.20-10.50am	13. Tien Peng, UCSF Stromal diversity and plasticity in the maintenance of organ function andfibrotic repair	听
10.55-11.30am	14.Tammy Chang, UCSF The Role of Focal Adhesion Kinase in Hepatic Fibrogenesis	听
11.35-12.10	15. Ori Maller, UCSF A reciprocal interplay between tissue fibrosis and tumor immunity in breast cancer	听
12.15-1.00pm	Lunch	听
听	Session 4. Emerging anti-fibrotic therapies - Chair: S. Porter (Fibrogen)	听
1.00-1.40pm	16. Bernard Coulie, Pliant听Therapeutics听听听 Developing target engagement and inhibition tools to de-risk the clinical development of a dual selective 伪v尾6/伪v尾1 integrin inhibitor in IPF and otherfibrotic diseases	听
1.45-2.25pm	17. Eduard Gorina, Fibrogen Pamrevlumab vs placebo in patients with IPF. Results of a Phase 2 Clinical Trial	听
2.30-3.10pm	18. Kenneth E. Lipson, Fibrogen Activity and mechanism of pamrevlumab (anti-CTGF) in a mouse radiation-induced lung fibrosis model	听
3.15-3.35pm	Coffee